Sains Ma1aysiana 25(2): 41-49 (1996)                                                                                           Sains Hayat/

                                                                                                                                                                 Life Sciences

Blue Deficiency in Patients with Diabetis Mellitus without

Retinopathy - its Clincial Implications

Sharanjeet- Kaur

Jabatan Optometri

Fakulti Sains Kesihatan Bersekutu

Universiti Kebangsaan Malaysia

Jalan Raja Muda 50300 Kuala Lumpur Malaysia

ABSTRACT

This study was conducted for 3 main purposes: 1) to determine if there was blue colour deficiency amongst diabetes mellitus (IDDM and NIDDM) patients without retinopathy, 2) to determine if the Dl5 test could be used to detect any colour vision defects amongst diabetics without retinopathy (all previous workers have used FM 100-Hue), and 3) to assess the performance of diabetics without retinopathy in detecting correct colour changes with the urine strip test. Thirty eight non-insulin dependent diabetes mellitus (NIDDM) and 30 insulin-dependent diabetes mellitus (IDDM) patients without retinopathy participated in this study. A control group of 23 normal subjects were also included in the study. Dl5 colour vision test was performed under daylight conditions. Colour dependent urine glucose test (Glukotest) was also performed on all subjects. The study showed that 47.1% of diabetics (47.4% NIDDM and 46.7% IDDM patients) without retinopathy had a blue colour deficiency. Amongst the diabetics with a blue colour deficiency, 25% of diabetics (22% of NIDDM and 28.6% of IDDM patients) failed to accurately match the strip colour with the comparison chart on the bottle.

ABSTRAK

Kajian ini dilakukan untuk 3 tujuan: I) untuk menentukan samada terdapat gangguan penglihatan warna biru dalam pesakit diabetes mellitus (IDDM dan NIDDM) tanpa retinopati, 2) untuk menentukan samada ujian penglihatan warna Dl5 boleh digunakan untuk mengesan defek penglihatan warna dalam pesakit diabetes tanpa retinopati (kesemua kajian terdahulu menggunakan ujian FM 100-Hue). dan 3) untuk menilaikan prestasi pesakit diabetik tanpa retinopati dalam mengesan perubahan warna yang betul dengan menggunakan ujian strip urin. Tiga puluh lapan pesakit dengan non-insulin dependent diabetes (NIDDM) dan 30 pesakit dengan insulin dependent diabetes (IDDM) tanpa retinopati menyertai kajian ini. Kumpulan kawalan mengandungi 23 orang subjek yang normal juga terlibat di dalam kajian ini. Ujian penglihatan warna Dl5 dilakukan di bawah cahaya daylight. Ujian glukos urin berasaskan warna (Glukotest) dilakukan ke atas semua subjek. Kajian menunjukkan 47.1% pesakit diabetes (47.4% pesakit NIDDM dan 46.7% pesakit IDDM) tanpa retinopati mengalami defisiensi warna biru. Dalam kumpulan diabetik dengan defisiensi warna biru, 25% pesakit diabetes (22.2% adalah pesakit NIDDM dan 28.6% adalah pesakit IDDM) gagal untuk memadankan dengan tepat warna strip dengan carta perbandingan warna di atas botol.

RUJUKAN/REFERENCES

Algan M., Ziegler O., Gehin P., Got 1., Raspiller A., Weber M., et al. 1989. Visual evoked potentials in diabetic patients. Diabetes Care 12: 227-229.                                     

Bresnick G.H., Crawford J. & Groo A. 1984. Urine testing inaccuracies among diabetic patients with colour vision deficiency. Colour Vision Deficiencies VII, ed. Veriest G., Dr W. The Hague, Boston, Lancaster: Junk Publishers.

Brante-Stewart J.M., Cant J.S. & Craig J.O. 1983. Colour vision in young diabetics. Doc Ophthalmol Proc Ser 39: 377-381.

Doft B.H., Kingsley L.A., Orchard T.J., Kuller L., Drash A. & Becker D. 1984. Glycemic control and Diabetic Retinopathy. Ophthalmology 91(7): 763-768.   

Hardy K.J., Scarpello J.H.B. & Foster D.H. 1995. Relation between blood glucose control over 3 months and color discrimination in insulin dependent diabetic patients without retinopathy. Br J Ophthalmol 79: 300.

Kinner P.R., Aspinall P.A. & Lakowski R. 1972. The diabetic eye and colour vision. Trans Ophthalmol Soc UK 92: 69-78.

Lakowski R., Aspinall P.A. & Kinnear P.R. 1972. Association between colour vision losses and diabetes mellitus. Ophthalmic Res 4: 145-159.

Mantyjarvim. 1987. Screening of colour vision defects in diabetic patients. Acta Ophthalmologica 65: 178-184.

Muntoni S., Serra A., Mascia C. & Songini M. 1982. Dyschromatopsia in diabetes mellitus and its relation to metabolic control. Diabetes Care 15: 620-625. Roy

M.S., Mcculloch C., Hanna A.K. & Mortimer C. 1984. Colour vision in long­ standing diabetes mellitus. Br. J Ophthalmol. 68: 215-217.