Sains Malaysiana 38(3): 365-369(2009)
Chemical Constituents from the Fruit
Peel of
Goniothalamus scortechinii
(Sebatian Kimia daripada Kulit Buah Goniothalamus scortechinii)
Aryanti Abdullah1, Zuriati Zakaria1, Fasihuddin B. Ahmad2, K. Mat-Salleh1 & Laily B. Din1*
1Faculty of Science and Technology, Universiti Kebangsaan
Malaysia
43600 Bangi, Selangor D.E., Malaysia
2Faculty of Resource Science and Technology
Universiti Malaysia Sarawak, 93400 Samarahan,
Sarawak
Malaysia
Received: 20 June 2008 / Accepted: 29 August 2008
ABSTRACT
The phytochemical investigation on
the fruit peel of Goniothalamus scortechinii (Selayar Raja Ubat) obtained from Gunung Stong, Kelantan has resulted in the isolation of five
compounds namely pinocembrine, altholactone, goniofufurone, goniotriol and goniopypyrone. Their structures were determined
extensive ultra violet (UV), infrared (IR),
nuclear magnetic resonance (NMR) spectroscopy and gas chromatography-mass
spectrum (GCMS) analysis.
Keywords: Altholactone; goniofufurone; goniotriol; goniopypyrone; Goniothalamus scortechinii; pinocembrine
ABSTRAK
Kajian fitokimia ke atas kulit
buah Goniothalamus scortechinii (Selayar Raja Ubat) yang diperolehi dari Gunung Stong, Kelantan telah berjaya memencilan lima
sebatian iaitu pinosembrin, altholakton, goniofufuron, goniotriol dan goniopipiron. Kesemua struktur
ditentukan dengan menggunakan teknik spektroskopi, ultra lembayung (UL),
inframerah (IM), resonans magnet nukleus (RMN) dan analisis kromatografi
gas-spektrum jisim (KGSJ).
Kata kunci: Altolakton; goniofufuron; goniotriol;
goniopipiron; Goniothalamus scortechinii; pinosembrin
REFERENCES
Din, L.B., Colgate, S.M. & Razak, D.A. 1990. Scorazanone,
a 1-aza-anthraquinone from Goniothalamus
scortechinii. Phytochemistry 29: 346-348.
Din, L.B., Said,
I.M., Salleh, K.M., Zakaria, Z., Azimahtol Hawariah, L.P., Ahmad, F.B., Latiff,
A., Yusoff, N.I., Samsudin, M.W. & Mohamed, R. 1997. Studies on Goniothalamus: A Malaysian
perspective. In Bioresource Utilization: The Biotechnology Option for
Malaysia
, Ismail, G. (ed) (pp. 147-150)P etaling Jaya: Pelanduk Publications (M) Sdn Bhd.
Dzulkifli, A.R., Gan,
E.K., Musa, M., Razak, L. & Sam, T.W. 1984.
Pharmaceutical evaluation of aqueous extract of Selayak Hitam: Teratogenic and possible abortification effect. Medical Journal of
Malaysia
39: 48-57.
El-Zayat, A.E., Ferigni, N.R., McCloud, T.G., McKenzie, A.T., Byrn, S.R., Cassady, J.M., Chang,
C.J. & McLaughlin, J.L. 1985. A
novel bioactive styryl-lactones:
tetrahydrofurano-2-pyrone from Goniothalamus giganteus (Annonaceae). Tetrahedron Letters 26: 955-956.
Fang, X.P.,
Anderson
, J.E., Chang, C.J., Fanwick, P.E. & McLaughlin, J.L. 1990. Novel bioactive styryllactones: goniofufurone, goniopypyrone and 8-acetylgoniotriol from Goniothalamus giganteus (Annonaceae). X-ray molecular structure of goniofufurone and of goniopypyrone. Journal of Chemical Society Perkin Transaction 1: 1655.
Fasihuddin, B.A., Ipor,
I.
& Laily, B.D. 1995.
Medicinal plants used by Kelabit community in Bario,
Sarawak
. In Chemical
Prospecting in the Malaysian Forest, Ismail, G. et al. (eds)
(pp. 43-46), Petaling Jaya, Pelanduk
Publications (M) Sdn.Bhd.
Jung, J.H., Pummangura, S., Chaichantipyuth, C., Patarapanich,
C. & McLaughlin, J.L. 1990. Bioactive constituents of Melodorum fruticosum. Phytochemistry 29(5): 1667-1670.
Saunders, R.M.K. 2003. Goniothalamus species (Annonaceae)
in Peninsular Malaysia. Botanical Journal
of the Linnean Society 142: 321-339.
Tsubuki, M., Kanai, K., Nagase, H.
& Honda, T. 1999. Stereocontrolled synthesis of
novel styryl lactones, (+) goniodiol,
(+)-goniotriol. (+)-8-acetylgoniotriol, (+)-goniofufurone, (+)-deoxygoniopypyrone,
(+)-goniopypyrone and (+) altholactone from common intermediates and cytotoxicity of their
congeners. Tetrahedron 55: 2493-2514.
Zakaria, M., Saito, I. & Matsuura, T. 1989. Aporphine alkaloids from Goniothalamus species. International Journal of Crude Drug 27: 92-94.
*Corresponding author; email: lbdin@ukm.my
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