Sains Malaysiana 48(12)(2019): 2693–2699
http://dx.doi.org/10.17576/jsm-2019-4812-10
Clinical and
Pathological Evaluation of Benign Skin Lesions
(Penilaian Klinikal dan
Patologi Lesi Kulit Benigna)
SABAHATTIN DESTEK1*
& VAHIT ONUR GUL2
1Department of General
Surgery, Bezmialem Vakıf University School of Medicine, 34093 Fatih,
Istanbul, Turkey
2Department of General
Surgery, Gulhane Education and Research Hospital, 06010 Etlik, Ankara, Turkey
Received: 13 February
2019/Accepted: 23 September 2019
ABSTRACT
Skin lesions are commonly benign in nature. The present study aims
to evaluate the prevalence and clinicopathological characteristics of a large
series of benign skin lesions (BSLs) excised in our clinic.
Patients with skin lesions who underwent total excisional biopsy at the general
surgery clinic between 2012 and 2016 were reviewed. A total of 551 patients
with BSLs were included in the study. Of these, 43.7% were
females and 56.7% were males. The age range was between 2 and 98 years with a
mean of 39.7 years. The most commonly occurring group of BSLs
was of the appendageal tumors (33.3%), and this finding was statistically
significant. The most common keratinocytic BSL (13.6%)
was verruca vulgaris. In the present study, various types of BSLs
and their occurrences were evaluated. Benign skin tumors can turn into
malignant types. A biopsy should be performed to establish the exact diagnosis.
We performed an excisional biopsy to confirm the diagnosis.
Keywords: Benign skin lesions; clinicopathological examination;
excisional biopsy
ABSTRAK
Lesi kulit adalah perkara biasa dan kebanyakannya lesi jinak.
Tujuan kajian ini adalah untuk menilai kelaziman dan ciri klinikopatologi siri
besar lesi kulit benigna yang dikeluarkan di klinik kami. Pesakit yang mengalami
lesi kulit dikaji semula, yang menjalani jumlah biopsi ekslusif dalam klinik
pembedahan umum antara 2012 dan 2016. Sejumlah 551 pesakit dengan lesi kulit
benigna termasuk dalam kajian ini. Daripada pesakit ini, 43.7% adalah wanita
dan 56.7% adalah lelaki. Julat umur adalah antara 2 dan 98 tahun dengan purata
39.7 tahun. Kumpulan yang paling biasa (33.3%) lesi kulit jinak adalah tumor
lampiran dan penemuan ini secara statistik secara signifikan. Lesi kulit yang
paling biasa (13.6%) adalah verruca vulgaris. Dalam kajian ini, pelbagai jenis
lesi kulit benigna dan frekuensi relatifnya dinilai. Tumor kulit benigna boleh
berubah menjadi jenis malignan. Biopsi perlu diambil untuk menentukan diagnosis
yang tepat. Kami melakukan biopsi pengecualian untuk diagnosis.
Kata kunci: Biopsi eksisi; lesi kulit benigna; pemeriksaan klinikopatologi
REFERENCES
Bas,
Y., Kalkan, G., Seckin, H.Y., Takcı, Z., Sahin, S. & Demir, A.K. 2014.
Analysis of dermatologic problems in geriatric patients. Turkish Journal of
Dermatology 8(4): 206-209.
Bertanha,
F., Nelumba, E.J., Freiberg, A.K., Samorano, L.P. & Neto, F.C. 2016.
Profile of patients admitted to a triage dermatology clinic at a tertiary
hospital in São Paulo, Brazil. Anais brasileiros de dermatologia 91(3):
318-325.
Choi,
S.H., Kim, K.H. & Song, K.H. 2016. Clinical features of cutaneous
premalignant lesions in Busan City and the Eastern Gyeongnam Province, Korea: A
retrospective review of 1,292Cases over 19 Years (1995~2013). Annals of
Dermatology 28(2): 172-178.
Edlich,
R.F., Becker, D.G., Long, W.B. & Masterson, T.M. 2004. Excisional biopsy of
skin tumors. Journal of Long-Term Effects of Medical Implants 14(3):
201-214.
Ferrándiz,
C., Malvehy, J., Guillén, C., Ferrándiz-Pulido, C. & Fernández-Figueras, M.
2017.Precancerous skin lesions. Actas Dermo-Sifiliográficas 108(1):
31-41.
Freak,
J. 2005. Identification of skin cancers 1: Benign and premalignant lesions. British
Journal of Community Nursing 10(1): 8-12.
Furue,
M., Yamazaki, S., Jimbow, K., Tsuchida, T., Amagai, M., Tanaka, T., Matsunaga,
K., Muto, M., Morita, E., Akiyama, M., Soma, Y., Terui, T. & Manabe, M.
2011. Prevalence of dermatological disorders in Japan: a nationwide,
cross-sectional, seasonal, multicenter, hospital-based study. The Journal of
Dermatology 38(4): 310-320.
Gogi,
A.M. & Ramanujam, R. 2013. Clinicopathological study and management of
peripheral soft tissue tumours. Journal of Clinical and Diagnostic Research 7(11):
2524-2526.
Higgins,
J.C., Maher, M.H. & Douglas, M.S. 2015. Diagnosing common benign skin
tumors. American Family Physician 92(7): 601-607.
Hwang,
S-M., Pan, H-C., Hwang, M-K., Kim, M-W. & Lee, J-S. 2016. Malignant skin
tumor misdiagnosed as a benign skin lesion. Archives of Craniofacial Surgery 17(2): 86-89.
Ingraffea,
A. 2013. Benign skin lesions. Facial Plastic Surgery Clinics of North
America 21(1): 21-32.
Kanitakis,
J. 2010. Adnexal tumours of the skin as markers of cancer-prone syndromes. Journal
of the European Academy of Dermatology and Venereology 24(4): 379-387.
Kartal,
D., Cinar, S.L., Akin, S., Ferahbas, A. & Borlu, M. 2015. Skin findings of
geriatric patients in Turkey: A 5-year survey. Dermatol Sinica 33(4):
196-200.
Kasraeian,
S., Allison, D.C., Ahlmann, E.R., Fedenko, A.N. & Menendez, L.R. 2010. A
Comparison of fine-needle aspiration, core biopsy, and surgical biopsy in the
diagnosis of extremity soft tissue masses. Clinical Orthopaedics and Related
Research 468(11): 2992-3002.
Kim,
H.S., Cho, E.A., Bae, J.M., Yu, D.S., Oh, S.T., Kang, H., Park, C.J., Lee,
J.D., Lee, J.Y.,Kim, S.Y., Kim, H.O. & Park, Y.M. 2010. Recent trend in the
incidence of premalignant and malignant skin lesions in Korea between 1991 and
2006. Journal of Korean Medical Science 25(6): 924-929.
Kyriakis,
K.P., Alexoudi, I., Askoxylaki, K., Vrani, F. & Kosma, E. 2012.
Epidemiologic aspects of seborrheic keratoses. International Journal of
Dermatology 51(2): 233-234.
Layfield,
L.J., Schmidt, R.L., Sangle, N. & Crim, J.R. 2014. Diagnostic accuracy and
clinical utility of biopsy in musculoskeletal lesions: A comparison of
fine-needle aspiration, core, and open biopsy techniques. Diagnostic
Cytopathology 42(6): 476-486.
LeBoit,
P.E. (Philip E); International Agency for Research on Cancer; World Health
Organization; International Academy of Pathology; European Organization for
Research on Treatment of Cancer; UniversitätsSpital Zürich Departement
Pathologie. 2006. Pathology and Genetics of Skin Tumours. Lyon: IARC
Press pp. 9-291.
Lee, E.H., Nehal, K.S.
& Disa, J.J. 2010. Benign and premalignant skin lesions. Plastic and
Reconstructive Surgery 125(5): 188e-198e.
Luba, M.C., Bangs, S.A.,
Mohler, A.M. & Stulberg, D.L. 2003. Common benign skin tumors. American
Family Physician 67(4): 729-738.
Mohammedamin, R.S., van
der Wouden, J.C., Koning, S., van der Linden, M.W., Schellevis, F.G., van
Suijlekom-Smit, L.W. & Koes, B.W. 2006. Increasing incidence of skin
disorders in children? A comparison between 1987 and 2001. BMC Dermatology 6:
4.
Murray, C.J., Lopez,
A.D., Black, R., Mathers, C.D., Shibuya, K., Ezzati, M., Salomon, J.A.,
Michaud, C.M., Walker, N. & Vos, T. 2007. Global burden of disease 2005:
Call for collaborators. Lancet 370(9582): 109-110.
Nguyen, T. & Zuniga,
R. 2013. Skin conditions: Benign nodular skin lesions. FP Essentials 407:
24-30.
Pujani, M., Madaan, G.,
Jairajpuri, Z., Jetley, S., Hassan, M. & Khan, S. 2016. Adnexal tumors of
skin: An experience at a tertiary care center at Delhi. Annals of Medical
and Health Sciences Research 6(5): 280-285.
Sinikumpu, S-P.,
Huilaja, L., Jokelainen, J., Koiranen, M., Auvinen, J., Hägg, P.M., Wikström,
E., Timonen, M. & Tasanen, K. 2014. High prevalence of skin diseases and
need for treatment in a middle aged population. A Northern Finland Birth Cohort
1966 Study. PLoS ONE 9(6): e99533.
Wakely, P.E. Jr. &
Kneisl, J.S. 2000. Soft tissue aspiration cytopathology. Cancer 90(5):
292-298.
Woon, D.T.S &
Serpell, J.W. 2008. Preoperative core biopsy of soft-tissue tumours facilitates
their surgical management: A 10 year update. ANZ Journal of Surgery 78(11):
977-981.
*Corresponding
author; email: dr.s.destek@gmail.com
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