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Sains Malaysiana 49(6)(2020): 1273-1282
http://dx.doi.org/10.17576/jsm-2020-4906-05
Ameliorative Effect of Apple Pomace and Mango Peels against
Hyperlipidemia and Lipid Peroxidation Induced by Hyperlipidemic Diet
(Kesan Amelioratif Buah Epal dan
Kulit Mangga terhadap Hiperlipidemia dan Peroksidasi Lipid disebabkan oleh Diet
Hiperlipidemik)
HUMA
UMBREEN1*, MUHAMMAD UMAIR ARSHAD1, RAZIA NOREEN2 & KIRAN AFTAB3
1Institute
of Home and Food Sciences, GC University, Faisalabad, Pakistan
2Department
of Biochemistry, GC University, Faisalabad, Pakistan
3Department
of Chemistry, GC University, Faisalabad, Pakistan
Received:
18 October 2018/Accepted: 17 February 2020
ABSTRACT
Diet
induced hyperlipidemia is a major cause for atherosclerosis, lipid
peroxidation, and fatty liver diseases. Fruit processing waste rich in dietary
fiber and antioxidant capacity can be an economical way to manage such risk
factors. The major objective of the present study was to manage hyperlipidemia
by including apple pomace and mango peels in daily diet. Dry powder obtained
from apple pomace, mango peels and their mixture was added to the normal chow
on replacement basis by 12%. These were fed to the rats along with
hyperlipidemic diet to the experimental groups (N=30, 10/group), while control
group (N=10) was fed hyperlipidemic diet alone. The rats were analyzed for
water and feed intake, body weight, organs to body weight ratio, glucose
concentration, lipid profile, lipid peroxidation test, liver cholesterol, and
liver and renal function tests. The results showed that high cholesterol in
diet was well managed by rat groups on apple pomace and mango peels supplement.
The mango peels powder was found to be more effective as compared to apple pomace
powder against hyperlipidemia. Mango peels and apple pomace powders not only
improved the lipid profile but also resulted in lower liver cholesterol
concentration and better lipid peroxidation status of the experimental rats as
compared to control group. It can be concluded that fruit processing waste
specially mango peels can be cost effective tool to manage diet induced
hyperlipidemia, lipid peroxidation and fatty liver diseases.
Keywords: Antioxidants; fiber; fruit
waste; lipid peroxidation; liver cholesterol
ABSTRAK
Diet
teraruh hiperlipidemia adalah penyebab utama aterosklerosis, peroksidasi lipid
dan penyakit hati berlemak. Serat pemakanan yang kaya dengan sisa pemprosesan
buah dan keupayaan antioksidan boleh dijadikan sebagai satu cara yang ekonomi
untuk menguruskan faktor risiko tersebut. Objektif utama kajian ini adalah
untuk menguruskan hiperlipidemia dengan memasukkan buah epal dan kulit manga
dalam diet harian. Serbuk kering yang diperoleh daripada buah epal, kulit manga
dan campuran tersebut telah ditambahkan ke dalam chow biasa secara penggantian
sebanyak 12%. Makanan diberikan kepada tikus dengan diet hiperlipidemik bagi
kumpulan uji kaji (N=30, 10/kumpulan), manakala kumpulan kawalan (N=10) diberi
makanan diet hiperlipedemik sahaja. Tikus dianalisis untuk pengambilan air dan
makanan, berat badan, nisbah berat organ kepada badan, kepekatan glukosa,
profil lipid, ujian peroksidasi lipid, kolesterol hati dan ujian fungsi hati
dan ginjal. Hasil kajian menunjukkan bahawa kolesterol tinggi dalam makanan
dapat dikendalikan dengan baik oleh kumpulan tikus dengan bahan tambahan buah
epal dan kulit mangga. Serbuk kulit mangga didapati lebih berkesan jika
dibandingkan dengan serbuk buah epal terhadap hiperlipidemia. Serbuk kulit
mangga dan buah epal bukan sahaja meningkatkan profil lipid tetapi juga
menghasilkan kepekatan kolesterol hati yang lebih rendah dan status peroksidasi
lipid yang lebih baik bagi tikus eksperimen berbanding dengan kumpulan kawalan.
Ini dapat disimpulkan bahawa sisa pemprosesan buah khususnya kulit mangga dapat
menjadi alat yang efektif daripada segi kos untuk menguruskan hiperlipidemia
yang disebabkan oleh diet, peroksidasi lipid dan penyakit hati berlemak.
Kata kunci: Antioksida; kolesterol hati;
peroksidasi lipid; serat; sisa buah
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*Corresponding author; email: huma_umbreen@yahoo.com
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