Sains Malaysiana 41(5)(2012): 585–590

Chemical Constituents of Garcinia prainiana

(Komposisi Kimia Garcinia prainiana)

Shukranul Mawa & Ikram M. Said*

School of Chemical Sciences & Food Technology, Faculty of Science and Technology

Universiti Kebangsaan Malaysiam 43600 Bangi, Selangor, D.E., Malaysia

Diserahkan: 16 September 2009 / Diterima: 18 November 2011

ABSTRACT

Five compounds identified as friedelin 1, eupha-8, 24- diene 3-β-ol 2, stigmasterol 3, teraxerone 4 and teraxerol 5 have been isolated from Garcinia prainiana (Guttiferae) for the first time. There has been no previous report on the chemical constituents and biological activities of this plant. Compounds 1, 2 & 3 were isolated from the methanol extract of the twigs while compounds 4 & 5 were isolated from the methanol extract of the leaves. The structures for all the compounds were evaluated based on spectroscopic analysis and comparison with the published information in the literature.

Keywords: Garcinia prainiana; Guttiferae; isolation; structure elucidation

ABSTRAK

Lima sebatian yang dikenal pasti sebagai friedelin 1, eupha-8, 24- diene 3-β-ol 2, stigmasterol 3, teraxerone 4 dan teraxerol 5 telah dipisahkan buat pertama kali daripada Garcinia prainiana (Guttiferae). Komposisi kimia dan aktiviti biologi ke atas G. prainiana belum pernah dilaporkan sebelum ini. Sebatian 1, 2 dan 3 telah dipisahkan daripada ekstrak metanol ranting manakala sebatian 4 dan 5 daripada ekstrak metanol daun. Struktur semua sebatian telah ditentukan dengan bantuan data spektroskopi dan perbandingan dengan data literatur.

Kata kunci: Garcinia prainiana; Guttiferae; pemisahan; penentuan struktur

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*Pengarang untuk surat-menyurat; email: kiam@ukm.my