Sains Malaysiana 45(5)(2016): 777–785
Dengue
Vector Control in Malaysia: A Review for Current and Alternative Strategies
(Kawalan
Vektor Denggi di Malaysia: Semakan Kajian Semasa dan Strategi Alternatif)
SONG-QUAN ONG*
Vector
Control Research Unit, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia
KDU University
College Penang, Jalan Anson, George Town, 10400 George Town,
Pulau Pinang,
Malaysia
Diserahkan:
13 April 2015/Diterima: 24 November 2015
ABSTRACT
Dengue is a major issue in Malaysia
as the dramatic emerge of infection. Yet an effective vaccine or
medicine is not yet available, although many attempts are undergoing.
Dengue vector control is still considered the most effective way
for controlling and preventing the transmission of dengue virus.
Nonetheless, as the conventional approaches are less successful
in managing the dengue transmission, it is time to review the current
applied and other available approaches. Current dengue vector relied
greatly on the chemical approach as space treatment either thermal
or ULV
fogging, however, the approach seem like under the
expectation. Beside space treatment, new control methods for example
biological control (bacterium Bacillus thuringiensis,
predatory mosquito Toxorhynchites) and attractive trap were
carried out at certain location of Malaysia. Moreover, new emerged
approaches such as mass release of genetic modification or artificially
Wolbachia infected male dengue vector for the objective of
generating sterile offspring when mate with wild population is urge
to be tested in Malaysia, although concerns have to be taken before
the actual mass release. In conclusion, control of dengue vector
shall not consist exclusively for a single approach, neither genetic
modification of artificially Wolbachia infected technique,
nor the conventional insecticidal treatment. It should, however,
comprise of the environment management as the fundamental approach,
a well-planned integrated control program and a good cooperation
among the organization.
Keywords: Aedes; dengue
control; dengue vector; Malaysia; strategies
ABSTRAK
Denggi merupakan isu yang penting di
Malaysia disebabkan oleh kemunculan jangkitan yang dramatik. Namun,
vaksin atau perubatan yang berkesan masih belum diperoleh walaupun
banyak cubaan sedang dijalankan. Kawalan vektor denggi masih dianggap
sebagai cara yang paling berkesan untuk mengawal dan mencegah penyebaran
virus denggi. Namun begitu, cara kawalan konvensional kurang berjaya
dalam pencegahan denggi; ia merupakan masa untuk mengkaji kaedah
sedia ada dan cara lain yang berpotensi. Kini, kawalan vektor denggi
sangat bergantung kepada kawalan kimia iaitu rawatan ruang sama
ada terma atau ULV fogging,
walau bagaimanapun, kaedah ini adalah di bawah jangkaan. Selain
rawatan ruang, kaedah kawalan seperti kawalan biologi (bakteria
Bacillus thuringiensis,
nyamuk pemangsa Toxorhynchites) dan perangkap telah dijalankan
di lokasi tertentu di Malaysia. Selain itu, kaedah baru yang muncul
seperti pelepasan populasi pengubahsuaian genetik ataupun infeksi
Wolbachia pada vektor denggi jantan dengan objektif untuk
menghasilkan anak yang disteril apabila disenyawakan dengan populasi
liar telah dicadangkan di Malaysia, walaupun pengawasan perlu diberi
perhatian sebelum pelepasan yang sebenar. Kesimpulannya, kawalan
vektor denggi tidak hanya terdiri daripada pendekatan tunggal atau
teknik modifikasi genetik infeksi buatan Wolbachia, ataupun
rawatan racun serangga konvensional. Ia sepatutnya terdiri daripada
pengurusan alam sekitar untuk vektor denggi sebagai kaedah asas,
program kawalan yang pelbagai dan dirancang dengan baik serta kerjasama
yang baik antara organisasi.
Kata
kunci: Aedes; kawalan denggi; Malaysia; strategi; vektor denggi
RUJUKAN
Abu Hassan,
A. 2014. Understanding Vector Biology of Dengue: Implication to Dengue Control
in Proceeding 2nd International Symposium on Insects,
Malaysia.
Abu Hassan,
A., Che Salman, M.R., Ngumbang, J., Ramli, A. & El-Badri, A.M. 2005.
Mosquitoes of urban areas of Penang abundance and control in Proceeding of
the 5th International Conference on Urban Pests.
Ali, A.,
Nayar, A. & Xue, R.D. 1995. Comparative toxicity of selected larvicides and
insect growth-regulators to a Florida laboratory population of Aedes
albopictus. Journal of the American Mosquito Control Association 11:
72-76.
Banu, S.,
Hu, W., Hurst, C., & Tong, S. 2011. Dengue transmission in the Asia-Pacific
region: impact of climate change and socio-environmental factors. Tropical
Medicine & International Health 16(5): 598-607.
Cheah, W.K.,
Ng, K.S., Marzilawati, A.R. & Lum, L.C.S. 2014. Review of dengue research
in Malaysia. Medical Journal of Malaysia 69: 59-67.
Christophides,
G.K., Gouagna, L.C., Jacobs-Lorena, M., James, A.A. & Olson, K. 2006. What
are relevant assays for refractoriness? In Bridging Laboratory and Field Research
for Genetic Control of Disease Vector, edited by Knols, B.G.J. & Louis, C. pp. 165-170.
Collins,
L.E. & Blackwell, A. 2000. The biology of Toxorhynchites mosquitoes
and their potential as biocontrol agents. Biocontrol News and Information 21(4):
105-116.
Crisis
Preparedness and Response Centre (CPRC). 2015. Bahagian Kawalan Penyakit Kebangsaan
Kementerian Kesihatan Malaysia (KKM) http://idengue.remotesensing.gov.my/
idengue/index.php. Accessed on 28 March 2015.
Elizabeth,
A.M. & Scott, L.O. 2013. Beyond insecticides: new thinking on an ancient
problem. Nature Reviews Microbiology 11: 181-193.
Focks, D.A.
1982. Toxorhynchites - a biological control agent of container-breeding
mosquitoes. AMCA Bulletin 6: 1-9.
Foo, A.E.S. & Yap,
H.H. 1982. Comparative bioassays of Bacillus thuringiensis H-14
formulations against 4 species of mosquitoes in Malaysia. Southeast Asian
Journal of Tropical Medicine and Public Health 13: 206-210.
Fu, G., Lees, R.S., Nimmo, D., Aw, D.,
Jin, L., Gray, P., Berendonk, T.U., White-Copper, H., Scaife, S., Phuc, H.K.,
Marinotti, O., Jasinskiene, N., James, A.A. & Alphey, L. 2010.
Female-specific flightless phenotype for mosquito control. In Proceeding National Academy of
Sciences USA 107:
4550-4554.
Gabrieli, P., Andrea, S. & Flaminia,
C. 2014. Engineering the control of mosquito-borne infectious diseases. Genome
Biology 15: 535.
Gerberg, E.J. & Visser, W.M. 1978.
Preliminary field trial for the biological control of Aedes aegypti by
means of Toxorhynchites brevipalpis, a predatory mosquito larva. Mosquito
News 38: 197-200.
Gubler, D.J. 2011. Dengue, urbanization
and globalization: The unholy trinity of the 21st century. Tropical Medicine
and Health 39(4): 3-11.
Gubler, D.J., Reiter, P., Ebi, K.L., Yap,
W., Nasci, R. & Patz, J.A. 2001. Climate variability and change in the
United States: potential impacts on vector- and rodentborne diseases. Environmental
Health Perspectives 109(2): 223-233.
Guzman, M.G., Halstead, S.B., Artsob, H.,
Buchy, P., Farrar, J., Gubler, D.J., Hunsperger, E., Kroeger, A., Margolis,
H.S., Martínez, E., Nathan, M.B., Pelegrino, J.L., Simmons, C., Yoksan, S.
& Peeling, R.W. 2010. Dengue: A continuing global threat. Nature Reviews
Microbiology 8(12 Suppl): S7-S16.
Hales, S., de Wet, N., Maindonald, J.
& Woodward, A. 2002. Potential effect of population and climate changes on
global distribution of dengue fever: an empirical model. Lancet 360(9336):
830-834.
Harris, A.F., Nimmo, D., Mckemey, A.R.,
Kelly, N., Scaife, S., Donnelly, C.A., Beech, C., Petrie, W.D. & Alphey, L.
2011. Field performance of engineered male mosquitoes. Nature Biotech.
29: 1034-1037.
Hedges, L.M., Brownlie, J.C., O’Neill,
S.L. & Johnson, K.N. 2008. Wolbachia and virus protection in
insects. Science 322(5902): 702.
Hii, Y.L., Rocklov, J., Ng, N., Tang,
C.S., Pang, F.Y. & Sauerborn, R. 2009. Climate variability and increase in
intensity and magnitude of dengue incidence in Singapore. Global Health Action. p. 2.
Hilgenboecker, K., Hammerstein, P.,
Schlattmann, P., Telschow, A. & Werren, J.H. 2008. How many species are
infected with Wolbachia? A statistical analysis of current data. FEMS
Microbiology Letters 281: 215-220.
Hoel, D.F., Kline, D.L. & Allan, S.A.
2009. Evaluation of six mosquito traps for collection of Aedes albopictus and
associated mosquito species in a suburban setting in North Central Florida. Journal
of the American Mosquito Control Association 25(1): 47-57.
Jones, C.J. 1993. Larval growth rates and
adult reproduction of Toxorhynchites splendens (Diptera: Culicidae) with
restricted dietary intake. Environmental Entomology 22: 174-182.
Kenawy, E.R. 1998. Recent advances in
controlled release of agrochemicals. Reviews in Macromolecular Chemistry
& Physics 38: 365-390.
Kumarasamy, V. 2006. Dengue fever in
Malaysia: time for review? Medical Journal of Malaysia 61(10): 1-3.
Laban, N.N. 2010. Comparative evaluation
of the MosquitoMagnet® trap and the CDC light trap as sampling tools for
outdoor mosquitoes. MSc. in Medical
Parasitology and Entomology. Jomo Kenyatta University of
Agriculture and Technology (Unpublished).
Lacroix, R., McKemey, A.R., Raduan, N.,
Kwee Wee, L., Hong Ming, W., Guat Ney, T., Rahidah, A.A.S., Salman, S.,
Subramaniam, S., Nordin, O., Hanum, A.T.N., Angamuthu, C., Marlina Mansor, S.,
Lees, R.S., Naish, N., Scaife, S., Gray, P., Labbé, G., Beech, C., Nimmo, D.,
Alphey, L., Vasan, S.S., Han Lim, L., Wasi, A.N. & Murad, S. 2012. Open field
release of genetically engineered sterile male Aedes aegypti in Malaysia.
PLoS ONE 7(8): e42771.
Laven, H. 1967. Eradication of Culex
pipiens fatigans through cytoplasmic incompatability. Nature 216:
383-384.
Lee, H.L. & Nazni, W.A. 2012. Updates
on genetically modified Aedes aegypti (L.) In Proceeding to
48th Annual Scientific conference of the Malaysia Society of Parasitology and
Tropical Medicine.
Lee, H.L. 2005. Germ warfare against mosquitoes.
What now? In Proceedings of the Fifth International Conference on
Urban Pests.
Lee, H.L., Antonietta, P.E., Seleena, P.
& Chiang, Y.F. 1997. Simultaneous ultra-low-volume application of
adulticide(malathion) and larvicide(Bacillus thuringiensis H-14) for the
control of dengue vectors. International Medical Research Journal 1:
13-19.
Lee, H.L. & Cheong, W.H. 1987. Field
evaluation of the efficacy of Bacillus thuringiensis H-14 for the
control of Aedes (Stegomyia) albopictus (Skuse). Mosquito-Borne
Disease Bulletin 3: 57-63.
Lee, H.L., Pe, T.H. & Cheong, W.H.
1986. Laboratory evaluation of the persistence of Bacillus thuringiensis var israelensis against Aedes
aegypti larvae. Mosquito-Borne Disease Bulletin 2: 61-66.
McMeniman, C.J. & O’Neill, L. 2010. A
virulent Wolbachia infection decreases the viability of the dengue
vector Aedes aegypti during periods of embryonic quiescence. PLoS
Neglected Tropical Diseases 4: e748.
McMeniman, C.J., Lane, R.V., Cass, B.N.,
Fong, A.W.C., Sidhu, M., Wang, Y.F. & O’Neill, S.L. 2009. Stable introduction of a
life-shortening Wolbachia infection into the mosquito Aedes aegypti. Science 323: 141-144.
Mohamad, N. & Zuharah, W.F. 2014.
Influence of container design on predation rate of potential biocontrol agent, Toxorhynchites
splendens (Diptera: Culicidae) against dengue vector. Tropical
Biomedicine 31(1): 166-173.
Mohammed, A. & Chadee, D.D. 2011.
Effects of different temperature regimens on the development of Aedes
aegypti (L.) (Diptera: Culicidae) mosquitoes. Acta Tropica 119: 38-43.
Natasha, E.A.M., Mikkel, B.Q. &
Annelies, W.S. 2013. Epidemiology of dengue: past, present and future
prospects. Clinical Epidemiology 5: 299-309.
National Biosafety Board Malaysia (NBBM).
2010. Fact sheet. Application for approval for limited markrelease-recapture of Aedes aegypti (L.) wild type and OX513A strains. NBB ref no:
NRE(S)609-2/1/3. Available: http://www.biosafety. nre. gov.my/consultation/fact
sheet.pdf. Accessed on 29 March 2015.
Nazni, W.A., Lee, H.L., Wan Rozita, W.M.,
Lian, A.C., Chen, C.D., Azahari, A.H. & Sadiyah, I. 2009. Oviposition
behaviour of Aedes albopictus in temephos and Bacillus thuringiensis
israelensis-treated ovitraps. Dengue Bulletin 33: 209-216.
Normile, D. 2013. Tropical medicine.
Surprising new dengue virus throws a spanner in disease control efforts. Science 342(6157): 415.
Nyamah, M.A., Sulaiman,
S. & Omar, B. 2011. Field observation on the efficacy of Toxorhynchites splendens (Wiedemann) as a biocontrol agent against Aedes albopictus (Skuse)
larvae in a cemetery. Tropical Biomedicine 28(2): 312-319.
Ong, S.Q. & Zairi, J. 2015.
Investigation of mosquito oviposition pheromone as lethal lure for the control
of Aedes aegypti (L.) (Diptera: Culicidae). Parasites & Vectors 8:
28.
Orduz, S., Restrepo, W., Patino, M.M.
& Rojas, W.W. 1995. Transfer of toxin genesto alternate bacterial hosts for
mosquito control. Memórias do Instituto Oswaldo Cruz 90: 97-107.
Patz, J.A. & Reisen, W.K. 2001.
Immunology, climate change and vector-borne diseases. Trends in Immunology 22(4):
171-172.
Phuc, H.K., Andreasen, M.H., Burton,
R.S., Vass, C., Epton, M.J., Pape, G., Fu, G., Condon, K.C., Scaife, S.,
Donnelly, C.A., Coleman, P.G., White-Cooper, H. & Alphey, L. 2007.
Late-acting dominant lethal genetic systems and mosquito control. BMC
Biology. 5: 11.
Qualls, W.A. & Mullen, G.R. 2007.
Evaluation of the mosquito magnet pro trap with and without 1-octen-3-ol for
collecting Aedes albopictus and other urban mosquitoes. Journal of
the American Mosquito Control Association 23(2): 131-136.
Rances, E., Ye, Y.H., Woolfit, M.,
McGraw, E.A. & O’Neill, S.L. 2012. The relative importance of innate immune
priming in Wolbachia-mediated dengue interference. PLOS Pathogens 8(2): e1002548.
Rawlins, S.C., Clark, G.G. &
Martinez, R. 1991. Effects of a single introduction of Toxorhynchites
moctezuma upon Aedes aegypti on a Caribbean Island. Journal of
the American Mosquito Control Association 7: 7-10.
Reeves, R.G., Denton, J.A., Santucci, F.,
Bryk, J. & Floyd, A. 2012. Standards and the regulation of genetically modified
insects. PLOS Neglected Tropical Diseases 6(1): e1502.
Reiter, P. 2001. Climate change and
mosquito-borne disease. Environmental Health Perspectives 109(1): 141-161.
Rose, R.I. 2009. A short note on the
final environmental impact statement-October 2008: use of genetically
engineered fruit fly and pink bollworm in APHIS plant pest control programs. Asia
Pacific Journal of Molecular Biology and Biotechnology 17: 87-91.
Scott, R. 2014. Rear and release: a new
paradigm for dengue control. Austral Entomology 53: 363-367.
Seleena, P., Lee, H.L. & Chiang, Y.F.
1999. Compatibility of Bacillus thuringiensis sero var israelensis and
chemical insecticides in the control of Aedes mosquitoes. Journal of
Vector Ecology 24: 216-223.
Seleena, P., Lee, H.L., Rohani, A.,
Nazni, W.A. & Khadri, M. 1996. Microdroplet application of mosquitocidal Bacillus
thuringiensis sing ultra-low-volume generator for the control of
mosquitoes. Southeast Asian Journal of Tropical Medicine and Public Health 27:
628-632.
Simmons, C.P., Farrar, J.J., Nguyen, V.
& Wills, B. 2012. Dengue. The New England Journal of Medicine 366(15):
1423-1432.
Susan, A. 2008. Genetically modified
mosquitoes. Nature Biotechnology 26: 725.
Tan, S.C. 2014. High-tech Mosquito Trap. The Star Online. Published on December 6,
2014 http://www.thestar.com.my/News/Community/2014/12/06/Hightech-mosquito-trap/.
Assessed on 10 March 2015.
Teixeira, L., Ferreira, A. &
Ashburner, M. 2008. The bacterial symbiont Wolbachia induces resistance
to RNA viral infections in Drosophila melanogaster. PLOS Biology 6(12):
e2.
Teoh, El Sen. 2014. Usage of 'elephant mosquitoes'
shows positive results in reducing Aedes. english.astroawani.com/malaysia-news/usage-elephant-mosquitoes-shows-positive-results-reducing-aedes-31234.
Assessed on 10 March 2015.
Tham, A.S. 2000. Issue and challenges in Aedes surveillance and control workshop proceeding behavior
intervention in dengue control of Malaysia Centre of Drug Malaysia. Universiti
Sains Malaysia and Institute of Health Promotion, Ministry of Health, Malaysia.
pp. 15-23.
Webster, D.P., Farrar, J. &
Rowland-Jones, S. 2009. Progress towards a dengue vaccine. Lancet Infectious
Diseases 9(11): 678-687.
Wilder-Smith, A. & Gubler, D.J. 2008.
Geographic expansion of dengue: the impact of international travel. Medical
Clinics of North America 92(6): 1377-1390.
Wilke, A.B. & Marrelli, M.T. 2012.
Genetic control of mosquitoes: population suppression strategies. Revista do
Instituto de Medicina Tropical de São Paulo. 54(5): 287-292.
Wise de Valdez, M.R., Nimmo, D., Betz,
J., Gong, H.F., James, A.A., Alphey, L. & Black, W.C. 2011. Genetic elimination
of dengue vector mosquitoes. In Proceeding National Academy of Sciences USA 108: 4772-4775.
WHO. 2006. Guideline for prevention and
control of dengue.
WHO. 2000. Scientific working group on
dengue. Meeting Report 3-5 April, 2000. http://apps.who.int/ tdr/ publications/tdr‑research‑publications/swg‑dengue/
pdf/ dengue‑swg.pdf.
WHO. 1997. Dengue Haemorrhagic Fever: Diagnosis, Treatment, Prevention and Control. 2nd ed. Geneva: World Health Organization.
WHO. 1995. Guidelines for dengue
surveillance and mosquito control.
Xue,
R.D., Doyle, M.A. & Kline, D.L. 2008. Field evaluation of CDC
and mosquito magnet X traps baited with dry ice, CO2 sachet,
and octenol against mosquitoes. Journal of the American Mosquito
Control Association 24(2): 249-252.
Yap,
H.H., Lee, Y.W. & Zairi, J. 2002. Indoor thermal fogging against vector
mosquitoes with two Bacillus
thuringiensis israelensis formulations, Vectobac ABG 6511 water-dispersible
granules and Vectobac 12AS liquid. Journal of the American Mosquito Control
Association 18: 52-56.
Zahari,
C.D. 2001. Workshop in Proceeding on Behaviour Intervention in Dengue Control
in Malaysia. Centre for Drug and research and School of Communication,
Universiti Sains Malaysia.
Zeichner,
B.C. & Peric, M.J. 1999. Laboratory testing of a lethal ovitrap for Aedes
aegypti. Medical and Veterinary Entomology 13: 234-238.
*Pengarang
untuk surat-menyurat; email: songguan26@gmail.com
|