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Sains Malaysiana 46(9)(2017): 1581–1586 http://dx.doi.org/10.17576/jsm-2017-4609-29
A New Cyclopentylidene and Other Chemical Constituents from
Malaysian Crotalaria pallida (Siklopentilidena Baru dan Juzuk Kimia Lain daripada Crotalaria
pallida Malaysia) SITI
RABEAH
FADZIL,
ANN-CHEE
YAP
& YEUN-MUN CHOO* Department of Chemistry, University of Malaya, 50603 Kuala Lumpur,
Federal Territory Malaysia
Diserahkan: 9 Januari 2017/Diterima: 18 Mac 2017 ABSTRACT Crotalaria pallida Aiton
is an herbaceous legume from the family Fabaceae. In the present
study, one new cyclopentyliene, crotolidene (1) and seven
known compounds, i.e. hydroxydihydrobovolide (2), octacosane
(3), trans-phytyl palmitate (4), linoleic
acid (5), methyl oleate (6), ethyl palmitate (7),
and palmitic acid (8) were isolated from the C. pallida
collected from Perak, Malaysia. These compounds were isolated
and characterized using extensive chromatographic and spectroscopic
methods. Keywords: Crotalaria pallida; crotolidene; cyclopentylidene; spectroscopic analysis;
(3E,5Z)-5-(4-hydroxy-2,2-dimethylcyclopentylidene)hex-3-en-2-one Crotalaria pallida Aiton
merupakan legum herba daripada famili Fabaceae. Satu siklopentilidena
baru, crotolidine (1) dan tujuh sebatian lain, iaitu
hidroksidihidrobovolide (2), octacosana (3), trans-phytil
palmitat (4), asid linoleik (5), metil oleat (6),
etil palmitat (7) dan asid palmitik (8) telah
diasingkan daripada C. pallida dari Perak, Malaysia.
Sebatian ini diasing dan dicirikan menggunakan kaedah kromatografi
dan spektroskopi. Kata kunci: Analisis
spektroskopi; Crotalaria pallida; crotolidene; siklopentilidena; (3E,5Z)-5-(4-hidroksi-2,2-dimetilsiklopentilidene)heks-3-en-2-on
RUJUKAN Abdullah, A.S. 1990. Poisonous Plants of Malaysia. Kuala Lumpur:
Tropical Press. Asand, M., Urixm, A.H. & Ahmad, V.U. 1991. Diterpene fatty acid
ester from Leucas nutans. J. Nat Prod. 54(5):
1444-1446. Chong, K.Y., Tan, H.T.W. & Corlett, R.T. 2009. A Checklist
of the Total Vascular Plant Flora of Singapore: Native, Naturalised
and Cultivated Species. Singapore: Raffles Museum of Biodiversity
Research, National University of Singapore. Farida Hanum, I. & Vander Maesen, L.J.G. 1997. Plant Resources
of South-East Asia No.11. Auxiliary Plants. Leiden: Backhuys
Publisher. Farnsworth, N.R., Wagner, H., Hoerhammer, L., Hoerhammer, H.P. &
Fong, H.H.S. 1968. Euphorbia esula. I. Preliminary phytochemical
and biological evaluation. J. Pharm. Sc. 57(6): 933-939.
Gunstone, F.D. 2007. 13C-NMR Spectroscopy of
Fatty Acids and Derivatives. The AOCS Lipid Library. http://lipidlibrary.aocs.
org/nmr/nmrmono/index.html. Gunstone, F.D. & Jacobsberg, F.R. 1972. Fatty acids, part 36
the synthesis, silver ion chromatographic, and NMR spectroscopic
properties of the nine 9,12-diunsaturated n-C18 acids. Chem.
Phy. Lipids. 9(2): 112-122. Joshi, H., Joshi, A.B., Sati, H., Gururaja, M.P., Shetty, P.R., Subrahmanyam,
E.V.S. & Satyanaryana, D. 2009. Fatty acids from Memecylon
umbellatum (Burm.). Asian J. Research Chem. 2(2):
178-180. Koshino, H., Yoshihara, T., Sakamura, S., Shimanuki, T., Sato, T.
& Tajimi, A. 1989. Novel C-ll epoxy fatty acid from stromata
of epichloe typhina on phleum pretense. Agric. Biol. Chem.
53(9): 2527-2528. Lawrie, W., McLean, J. & Younes, M.E.G. 1968. Constituents of
the seeds of Heracleum sphondylium. Phytochemistry
7(11): 2065-2066. Miranda-Vilela, A.L. & Grisolia, C.K. 2009. Characterization
of the major nutritional components of Caryocar brasiliense
fruit pulp by NMR spectroscopy. Quim. Nova. 32(9):
2310- 2313. Rajkumar, S. & Jebanesan, A. 2004. Mosquitocidal activities of
octacosane from Moschosma polystachyum Linn. (lamiaceae).
J. Ethnopharmacology 90: 87-89. Rakoff, H., Weisleder, D. & Emken, E.A. 1979. 13C-Nuclear
magnetic resonance of mono- and dihydroxy saturated and unsaturated
fatty methyl esters. Lipids 14(1): 81-83. Sigma-Aldrich. 1H NMR of Octacosane. 17 March 2017. Retrived
from http://www.sigmaaldrich.com/catalog/product/aldrich/ o504?lang=en®ion=MY
Speight, R.J., Rourke, J.P., Wong, A., Barrow, N.S., Ellis, P.R.,
Bishop, P.T. & Smith, M.E. 2011. 1H and 13C
solution- and solid-state NMR investigation into wax products
from the Fischer-Tropsch process. Solid State Nuclear Magnetic
Resonance 39: 58-64. Williams, M.C. & Molyneux, R.J. 1987. Occurrence, concentration,
and toxicity of pyrrolizidine alkaloids in crotalaria seeds.
Weed Science 35(4): 476-481. Wu, J., Tsujimori, M., Hirai, H. & Kawagishi, H. 2011. Novel
compounds from the mycelia and fruiting bodies of Climacodon
septentrionalis. Biosci. Biotechnol., Biochem. 75(4):
783-785. Yuan, W., Cheng, A., Fu, W., Zhao, M., Li, X., Cai, Y., Dong, J.,
Huang, K., Gustafson, K.R. & Yan, P. 2016. Structurally
diverse metabolites from the soft coral Sinularia verruca
collected in the South China Sea. J. Nat Prod. 79(4):
1124- 1131. *Pengarang untuk surat-menyurat; email: ymchoo@um.edu.my
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