Sains Malaysiana 47(3)(2018):
511–515
http://dx.doi.org/10.17576/jsm-2018-4703-10
Glyceryl Ether (mono-tert-butoxypropanediol)
in Emulsion System
(Eter Gliseril (mono-tert-butoksipropanadiol)
dalam Sistem Emulsi)
YUSRABBIL AMIYATI YUSOF1*, AZHAR ARIFFIN2 & ZAFARIZAL ALDRIN
AZIZUL HASAN1
1Consumer Product
Development Unit, Advanced Oleochemical Technology Division, Malaysian Palm Oil
Board, 6, Persiaran Institusi, Bandar Baru Bangi, 43000 Kajang, Selangor Darul
Ehsan
Malaysia
2Chemistry Department,
Faculty of Science, University of Malaya, Lembah Pantai , 50603 Kuala Lumpur,
Federal Territory, Malaysia
Diserahkan: 2 Ogos 2017/Diterima:
20 September 2017
ABSTRACT
This paper reports the effects of glyceryl
ether specifically mono-tert-butoxypropanediol
on oil in water emulsion system. Based on 12 HLB value,
screening for stable emulsions was carried out without the presence
of glyceryl ether. A stable emulsion was used as a control. Then
the effects of glyceryl ether on the emulsion system were investigated.
The emulsions prepared were analyzed for stability, viscosity, pH
value, particle size, in vitro dermal irritation potential,
in vitro ocular irritation potential and also moisturizing
property. The incorporation of glycerol in the emulsion system was
also done for comparison. Emulsions with glyceryl ether showed lower
viscosity values than emulsions with glycerol. Furthermore, the
emulsions also exhibited moisturizing property compared to the control
emulsion. Glyceryl ether is suitable to be used in cosmetic products
which require reduced viscosity but retain its skin hydration property.
Keywords: Diol; emulsion; glyceryl
ether
ABSTRAK
Kertas ini melaporkan kesan eter gliserol
khususnya mono-tert-butoksipropanadiol terhadap sistem
emulsi minyak dalam air. Berdasarkan nilai HLB 12, saringan untuk mendapatkan
emulsi yang stabil telah dijalankan tanpa kehadiran eter gliserol.
Emulsi yang stabil tersebut telah digunakan sebagai kawalan. Kemudian
kesan eter gliserol pada sistem emulsi telah dikaji. Emulsi tersebut
dianalisis untuk kestabilan, kelikatan, nilai pH, saiz zarah, potensi
kerengsaan kulit in vitro,
potensi kerengsaan okular in vitro dan sifat pelembapan.
Penggunaan gliserol dalam sistem emulsi juga telah dilakukan untuk
perbandingan. Emulsi yang mengandungi eter gliserol mempunyai nilai
kelikatan yang lebih rendah daripada emulsi yang mengandungi gliserol.
Emulsi tersebut juga mempamerkan sifat pelembapan berbanding kawalan.
Eter gliserol sesuai untuk digunakan dalam produk kosmetik yang
memerlukan kelikatan yang rendah tetapi masih mengekalkan ciri penghidratan
kulit.
Kata
kunci: Diol; emulsi; eter gliserol
RUJUKAN
Aghel, N., Moghimipour,
E. & Raies, A. 2007. Formulation of a herbal shampoo using total saponins
of Acanthophyllum Squarrosum. Iranian
Journal of Pharmaceutical Research 6(3): 167-172.
Alber, C.,
Buraczewska-Norin, I., Kocherbitov, V., Saleem, S., Lodén, M. & Engblom, J.
2014. Effects of water activity and low molecular weight humectants on skin
permeability and hydration dynamics - a double-blind, randomized and controlled
study. International Journal of Cosmetic Science 36: 412-418.
Ayoub, M. &
Abdullah, A.Z. 2012. Critical review on the current scenario and significance
of crude glycerol resulting from biodiesel industry towards more sustainable
renewable energy industry. Renewable and Sustainable Energy Reviews 16:
2671-2686.
Baranda, L.,
Gonzalez-Amaro, R., Torress-Alvarez, B., Alvarez, C. & Ramirez, V. 2002.
Correlation between pH and irritant effect of cleansers marketed for dry skin. International
Journal of Dermatology 41: 494-499.
Berardesca, L., Masson,
P., Rodrigues, L., Gummer, C.L., Léυéque, Loden, M., Piérard, G., Rogiers,
V., Salter, D., Sauermann, G., Serup, J. & Treυethan, M.A. 1997. EEMCO
guidance for the assessment of stratum corneum hydration: Electrical methods. Skin
Research and Technology 3: 126- 132.
Blute, I., Kronberg, B.,
Svensson, M. & Unelius, R. 1998. Phase-behaviour of alkyl glycerol ether
surfactants. Tenside Surfactant Detergent 35(3): 207-212.
Dobos, K. 2014. How
do Skin Moisturizers Work? http:// chemistscorner.com/how-do-skin-moisturizers-work/.
Accessed on 18 December 2014.
Fukuda, K., Soderman,
O., Lindman, B. & Shinoda, K. 1993. Microemulsions formed by alkyl polyglycosides
and an alkyl glycerol ether. Langmuir 9(11): 2921-2925.
Heming, M. 1999. The
World Glycerine Market. CTVO-Networkshop. HB International.
http://www.dainet.de/fnr/ ctvo/byproducts/heminghbi.doc. Accessed
on 2 January 2008.
Ismail, A.R., Wan Nurul
Fatihah, W.Y., Rusli, D. & Hazimah, A.H. 2014. Effect of glycerol derived
co-surfactant on the ternary phase behaviour of palm-based microemulsions. Journal
of Oil Palm Research 26(3): 240-250.
Ismail, R., Yusof, N.Z.,
Aldrin, Z. & Hassan, H.A. 2013. Safety assessment of oil palm phenolics as
active ingredient for topical application. Journal of Oil Palm Research 25(2):
188-196.
Jungermann, E. &
Sonntag, N.O.V. 1991. Cosmetic Science and Technology Series. Vol 11.
Glycerine: A Key Cosmetic Ingredient. New York: Marcel Decker, Inc.
Kanagaratnam, S., Hoque,
M.E., Sahri, M.M. & Spowage, A. 2013. Investigating the effect of deforming
temperature on the oil-binding capacity of palm oil based shortening. Journal
of Food Engineering 118: 90-99.
Knothe, G., Gerpen, J.V.
& KrahL, J. 2005. The Biodiesel Handbook. Urbana, Illinois: AOCS
Press.
Kuentz, M. &
Röthlisberger, D. 2003. Rapid assessment of sedimentation stability in
dispersions using near infra red transmission measurements during
centrifugation and oscillatory rheology. European Journal of Pharmaceutics
and Biopharmaceutics 56(3): 355-361.
Loo, C.H., Ismail, R.,
Basri, M., Lau, H.L.N., Tejo, B.A., Hassan, H.A., Choo, Y.M. & Kanthimathi,
M.S. 2014. Nanostructured lipid carriers (NLC) for efficient delivery of palm
phytonutrients. Journal of Oil Palm Research 26(3): 232-239.
Patel, M., Crank, M., Dornburg,
V., Hermann, B., Roes, L., Husing, B., Overbeek, L., Terragni, F.
& Recchia, E. 2006. Medium and long-term opportunities and risks
of the biotechnological production of bulk chemicals from renewable
resources - The potential of white biotechnology. The BREW project.
www.bio-economy.net/applications/files/Brew project report. pdf.
Accessed on 11 May 2010.
Peterman, W. 2011. Uses
of Glycerine. http://www.livestrong. com/article/63424-uses-glycerine/.
Accessed on 1 August 2013.
Rieger, M.M. &
Rhein, L.D. 1997. Surfactant Science Series, Volume 68, Surfactants in
Cosmetics (2nd ed., Revised and Expanded). New York: Marcel Dekker, Inc.
Sina, J.F., Galer, D.M.,
Sussman, R.G., Gautheron, P.D., Sargent, E.V., Leong, B., Shah, P.V., Curren,
R.D. & Miller, K. 1995. A collaborative evaluation of seven alternatives to
the Draize eye irritation test using pharmaceutical intermediates. Fundamental
and Applied Toxicology 26: 20-31.
Yusof, Y.A., Bakar, R.A.,
Lye, O.T. & Ahmad, S. 2010. A process for producing etherified
compounds from alcohol. MY-142751-A.
Zafarizal Aldrin, A.H.,
Ismail, R. & Ahmad, S. 2005. Safety evaluation for dermal and ocular
irritation of palm dihydroxystearic acid as a cosmetics ingredient. Journal
of Oil Palm Research 17: 160-167.
*Pengarang untuk surat-menyurat; email: amiyati@mpob.gov.my
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