The Malaysian Journal of Analytical Sciences Vol 13 No 1 (2009): 129 – 135

 

 

 

SYNTHESIS AND FLUOROMETRIC ANALYSIS OF SELECTED DIAZINE DERIVATIVES AND THEIR METAL COMPLEXES

 

Edura Badaruddin¹, Zaharah Aiyub², Zanariah Abdullah², Shah Bakhtiar Nasir²

 

¹Chemistry Division, Centre for Foundation Studies In Science,

²Department of Chemistry, Faculty of Science,

University of Malaya, 50603 Kuala Lumpur, Malaysia

 

Abstract

2-N-anilinopyrimidine, 2-N-methylanilinopyrimidine and 2-N-ethylaminopyrimidine were obtained when commercially available 2-chloropyrimidine was refluxed with aniline, N-methylaniline and ethylamine respectively. Each ligand was then reacted with Cr(II) acetate to give their respective complexes. The structures of the ligands and complexes were confirmed by spectroscopic analysis. Fluorometric analysis of metal complexes of pyrimidine derivatives and the ligand itself were carried out in a quartz cell using methanol as the solvent. The compounds each exhibited fluorescence characteristic with the ligands. The ligands, in general, showed a high relative intensity and the fluorescence peak were also shifted to the lower wavelength compared to their metal complexes.

 

Keywords: fluorescence, pyrimidine derivatives, metal complexes

 

References

1.       N. Saha and S. K. Kar. J. Inorg. Nucl. Chem. 39 (1977), p. 195.

2.       D. T. Hurst, The Chemistry and Biochemistry of Pyrimidines, Purines and Pteridents, Wiley, New York, 1980.

3.       E. Wehry, L. Rogers, “Fluorescence and Phosphorescence Analysis” , Interscience, New York, 1966.

4.       Z. Abdullah, PhD Thesis (1989), Queen Mary & Westfield College, Uni. Of London.

5.       M. R. Provenzano, V. D'Orazio, M. Jerzykiewicz and N. Senesi, Chemosphere, 55 (6), (2004).

6.       A.W. Varnes, R. B. Dodson and E. L. Wehry, J. Am. Chem. Soc. 94 (1972), p. 94.

7.       J. A. Kemlo and T. M. Sheperd, Chem. Phys. Lett. 47 (1977), p. 158.

8.       S. G. Schulman, Fluorescence and Phosphorescence Spectroscopy : Physicochemical Principles and Practice, Pergamon Press, New York, 1977.

9.       Aiyub, Z., Abdullah, Z., Yaacob, B. H. and Bakar, M. A. A. (2007) Malaysian Journal of Analytical Sciences 11(1): 105-109.

10.    Badaruddin, E., Aiyub, Z. and Abdullah, Z. (2008) Malaysian Journal of Analytical Sciences 12(2): 285-290.