Sains Malaysiana 39(3)(2010): 445–451

Alkaloids and Sulphur-containing Amides from Glycosmis

citrifolia and Glycosmis elongata

(Alkaloid dan Amida Mengandungi Sulfur daripada Glycosmis citrifolia dan Glycosmis elongata)

Mawardi Rahmani*, Rosmiati Muhammad Serang, Najihah Mohd Hashim, Mohd Aspollah Sukari & Gwendoline C.L. EE

Department of Chemistry Universiti, Putra Malaysia 43400 UPM, Serdang, Selangor D.E,. Malaysia

Abdul Manaf Ali

Department of Biotechnology, Universiti Putra Malaysia 43400 UPM

Serdang, Selangor D.E. Malaysia

Hazar Bebe Mohd Ismail

Centre for Foundation Study in Science, Universiti Malaya 59100 Kuala Lumpur, Malaysia

Received: 13 August 2009 / Accepted: 14 October 2009

ABSTRACT

Air-dried leaves of both Glycosmis citrifolia and Glycosmis elongata collected from Bogor Botanical Garden, Indonesia were individually extracted with chloroform to give dark viscous extracts after solvent removal. Column chromatographic separation of the extract of G. citrifolia yielded 5(6)-glutene-3α-ol, two sets conformers, (E)-dambullin and (Z)-dambullin, and (E)-methyldambullin and (Z)-methyldambullin. Similar treatment of the extract of G. elongata gave skimmianine and arborinine. The structures of the compounds were elucidated based on spectroscopic data and comparison with published reports.

Keywords: Arborinine; dambullin and methyldambullin; Glycosmis citrifolia; Glycosmis elongata; skimmianine

ABSTRAK

Daun kering kedua-dua Glycosmis citrifolia dan Glycosmis elongata yang dikutip dari Taman Botani Bogor, Indonesia telah diekstrak secara berasingan dengan kloroform untuk menghasilkan ekstrak gelap dan liat setelah penyejatan pelarutnya. Pemisahan melalui kromatografi turus terhadap ekstrak G. citrifolia menghasilkan 5(6)-gluten-3α-ol, dua set konformer, (E)-dambullin dan (Z)-dambullin, dan (E)-metildambullin dan (Z)-metildambullin. Menggunakan pendekatan yang sama terhadap ekstrak G. elongata telah mnghasilkan skimmianina dan arborinina. Semua sebatian telah ditentukan strukturnya berpandukan data spektroskopi dan perbandingan dengan rujukan.

Kata kunci: Arborinina; dambullin dan metildambullin; Glycosmis citrifolia; Glycosmis elongata; skimmianina 

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*Corresponding author; e-mail: mawardi@science.upm.edu.my