Sains Malaysiana 44(10)(2015): 1453–1459

Microsatellite DYS385 Polymorphism among the Tai and Mon-Khmer Speaking Populations of Northern Thailand

(Polimorfisme Mikrosatelit DYS385 antara Populasi Penutur Tai dan Mon-Khmer di Utara Thailand)

JATUPOL KAMPUANSAI* & SIRIWADEE CHOMDEJ

Department of Biology, Faculty of Science, Chiang Mai University, 50202, Thailand

Received: 8 December 2014/Accepted: 22 June 2015

ABSTRACT

Microsatellite DYS385 is a highly polymorphic marker in the Y chromosome. It has been used for investigating population genetic structure and personal identification in various ethnic groups of the world. This research aimed to analyze the microsatellite DYS385 polymorphism among 9 Tai and 11 Mon-Khmer speaking populations of northern Thailand. Fifty-six different haplotypes were found in 453 samples from 20 populations. Haplotype diversities and discrimination powers of populations belonging to the Tai linguistic family was higher than those of the Mon-Khmer group. Genetic affinities based on DYS385 variation do not conform to linguistic classification but a fraction of genetic divergence patterns can be explained by geographic distances.

Keywords: DYS385; genetic polymorphism; microsatellite; Mon-Khmer; Tai

ABSTRAK

Mikrosatelit DYS385 adalah petanda polimorfik tertinggi dalam kromosom Y. Ia telah digunakan bagi mengkaji struktur genetik dan pengenalan peribadi dalam pelbagai kumpulan etnik di dunia. Kajian ini bertujuan untuk menganalisis polimorfisme mikrosatelit DYS385 antara populasi penutur 9 Tai dan 11 Mon-Khmer di Utara Thailand. Lima puluh-enam jenis haplo berbeza ditemui dalam 453 sampel daripada 20 populasi. Kepelbagaian jenis haplo dan kuasa diskriminasi populasi tergolong dalam keluarga linguistik Tai adalah lebih tinggi berbanding kumpulan Mon-Khmer. Afinisi genetik berdasarkan variasi DYS385 tidak mematuhi klasifikasi linguistik tetapi sebahagian kecil daripada pola perbezaan genetik dapat dijelaskan oleh jarak geografi.

Kata kunci: DYS385; Genetik polimorfisme; mikrosatelit; Mon-Khmer; Tai

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*Corresponding author; email: Jatupol.k@cmu.ac.th