Sains Malaysiana 44(3)(2015): 365–370

Isolation and Characterization of Styryllactone of Goniothalamus ridleyi

(Pemencilan dan Pencirian Stirillakton Goniothalamus ridleyi)

SAMSIAH JUSOH^1,4, ZURIATI ZAKARIA², FASIHUDDIN B. AHMAD³ & LAILY B. DIN⁴*

¹Rice and Industrial Crop Research Centre, Malaysian Agricultural Research and Development Institute(MARDI), P.O. Box 12301, 50774 Kuala Lumpur, Malaysia

²Malaysia Japan Institute of Technology, Universiti Teknologi Malaysia, 54100 Kuala Lumpur

Malaysia

³Department of Chemistry, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia

⁴School of Chemical Sciences and Food Technology, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor Darul Ehsan, Malaysia

Received: 4 October 2013/Accepted: 4 September 2014

ABSTRACT

Phytochemical studies were conducted on the stem bark, stem, root and fruit of Goniothalamus ridleyi (Annonaceae) collected at Post Brooke, Gua Musang, Kelantan, Malaysia. Extraction using organic solvent followed by extensive purification using standard procedure afforded an epoxystyryllactone, 5-acetoxyisogoniothalamin oxide (1) from the stem bark and fruit; a styryllactone, 5-acetoxygoniothalamin (2) and a styrylpyrone, dehydrogoniothalamin (3) from the stem and root; a styryllactone, 5-hydroxygoniothalamin (4) from the root and styrylpyrone as well as goniothalamin (5) from the fruit. These compounds were characterized using spectroscopic techniques.

Keywords: Annonaceae; goniothalamin derivatives; Goniothalamus; NMR

ABSTRAK

Kajian fitokimia telah dijalankan ke atas kulit batang, batang, akar dan buah Goniothalamus ridleyi (Annonaceae) yang diperoleh dari Post Brooke, Gua Musang, Kelantan, Malaysia. Pengekstrakan menggunakan pelarut organik diikuti dengan pemisahan ekstensif menggunakan prosedur piawai menghasilkan epoksistirillakton, 5-asetoksiisogoniotalamin oksida (1) daripada kulit batang dan buah; stirillakton, 5-asetoksigoniotalamin (2) dan stirilpiron, dehidrogoniotalamin (3) daripada batang dan akar; stirillakton, 5-hidroksigoniotalamin (4) daripada akar dan stirilpiron manakala goniotalamin (5) daripada buah. Sebatian-sebatian ini dikenal pasti menggunakan teknik spektroskopi.

Kata kunci: Annonaceae; Goniothalamus; NMR; terbitan goniothalamin

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*Corresponding author; email: lbdin@ukm.edu.my