Sains Malaysiana 50(11)(2021): 3383-3394

http://doi.org/10.17576/jsm-2021-5011-22

Novel Deproteinized Natural Rubber Latex Adhesive Used in Extraoral Maxillofacial Prostheses

(Perekat Lateks Getah Asli Ternyahprotein Baharu yang Digunakan dalam Prostesis Maksilofasial Ekstraoral)

PAWEENA KONGKON¹, WIWAT PICHAYAKORN² & SASIWIMOL SANOHKAN¹*

¹Department of Prosthetics Dentistry, Faculty of Dentistry, Prince of Songkla University, Songkhla 90112

Thailand

²Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla 90112, Thailand

Received: 5 January 2021/Accepted: 8 March 2021

ABSTRACT

This study aimed to develop an adhesive for silicone maxillofacial prostheses and compared the properties with the Daro adhesive hydrobond (Factor II, Inc, Lakeside, AZ, USA). Two adhesives were developed from non-vulcanized natural rubber-based adhesives (Adhesive A) and deproteinized natural rubber latex (DNRL) products (Adhesive B) and stored at 4 °C. The Control group was the commercial Daro adhesive hydrobond (Factor II, Inc, Lakeside, AZ, USA). The physical properties (appearance, viscosity, spreadability, color, and pH) of the adhesives were measured and every week for 12 weeks after storing at 4 °C. The adhesives were characterized under scanning electron microscopy. Mechanical testing done were peel bond strength and biocompatibility testing was done using MTT assay. Physical, surface, and mechanical properties were compared with the commercial adhesive. Data analysis was done using SPSS version 24. Both adhesives were physically and chemically stable at temperature 4 °C and had suitable peel bond strength adhesives as the commercial adhesive. Hence, the adhesives can be used to adhere to the maxillofacial silicone prostheses.

Keywords: Deproteinized natural rubber; latex adhesive; maxillofacial silicone elastomer; rubber-based adhesives

ABSTRAK

Matlamat kajian ini ialah untuk membangunkan perekat prostesis maksilofasial silikon dan membandingkan sifatnya dengan perekat hidrobond Daro (Factor II, Inc., Lakeside, AZ, USA). Dua jenis perekat telah dibangunkan daripada perekat berjenis getah asli tak tervulkan (perekat A) dan lateks getah asli ternyahprotein (DNRL) (perekat B) dan disimpan pada suhu 4 °C. Sifat fizikal (penampilan, kelikatan, kebolehsebaran, warna dan pH) perekat telah diukur. Sampel perekat telah dicirikan menggunakan mikroskop imbasan elektron. Ujian mekanik (kekuatan ikatan kupasan dan kebioserasian) telah dilakukan menggunakan MTT asai. Sifat fizikal, permukaan dan mekanik sampel telah dibandingkan dengan perekat komersial. Analisis data telah dilakukan menggunakan SPSS versi 24. Didapati kedua-dua sampel perekat stabil pada suhu 4 °C dan mempunyai kekuatan ikatan kupasan yang setara dengan perekat komersial. Oleh itu, perekat yang dibangunkan sesuai digunakan dalam rekatan prostesis maksilofasial.

Kata kunci: Elastomer silikon maksilofasial; getah semula jadi ternyahprotein; perekat jenis getah; perekat lateks

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*Corresponding author; email: sanohkan.psu@gmail.com